What is ALS Disease?
ALS (Amyotrophic Lateral Sclerosis), also known as Lou Gehrig’s Disease, is an incurable fatal neuromuscular disease characterized by progressive muscle weakness, resulting in paralysis.Amyotrophic Lateral Sclerosis is a form of motor neuron disease. ALS, sometimes called Maladie de Charcot, is a progressive, neurodegenerative disease caused by the degeneration of motor neurons, the nerve cells in the central nervous system that control voluntary muscle movement.The disorder causes muscle weakness and atrophy throughout the body as both the upper and lower motor neurons degenerate, ceasing to send messages to muscles. Unable to function, the muscles gradually weaken, develop fasciculations ( muscle twitches) because of denervation ( loss of nerve supply ) and eventually atrophy ( is the partial or complete decrease in size or wasting away of a part of the body ) because of that denervation. The patient may ultimately lose the ability to initiate and control all voluntary movement; bladder and bowel sphincters and the muscles responsible for eye movement are usually spared.Over time, Lou Gehrig’s disease causes these motor neurons in the brain and spinal cord to shrink and disappear, so that the muscles no longer receive signals to move. As a result, the muscles become smaller and weaker, gradually the body becomes paralyzed